Structural Studies of Adenovirus Type 2 and an Assembly Mutant
نویسندگان
چکیده
منابع مشابه
Characterization of an early temperature-sensitive and cytocidal double mutant of adenovirus type 2.
Human adenovirus type 2 mutant, H2 ts 111, presented a double phenotype: temperature-sensitive (ts) for initiation and elongation of DNA synthesis, and cytocidal (cyt) by its large-plaque formation and the nucleolytic cleavage of both viral and cellular DNAs. Both characters were recessive since they were efficiently complemented by wild-type or other DNA-negative ts mutants. H2 ts 111 DNA--ter...
متن کاملpostnatal studies of bats (pipistrellus kuhlii and miniopterus schreibersii) & histomorphology and histochemistry studies of organs and diseases of (neurergus microspilotus and n. kaiseri)
1. to determine whether difference in birth body mass influenced growth performance in pipistrellus kuhlii we studied a total of 12 captive-born neonates. bats were assigned to two body mass groups: light birth body mass (lbw: 0.89 ± 0.05, n=8) and heavy birth body mass (hbw: 1.35 ± 0.08, n=4). heavier body mass at birth was associated with rapid postnatal growth (body mass and forearm length) ...
the investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
An adenovirus expressing mutant p27 showed more potent antitumor effects than adenovirus-p27 wild type.
The main inhibitory action of p27, a cyclin-dependent kinase inhibitor (CDKI), arises from its binding with the cyclin E/cyclin-dependent kinase 2 (Cdk2) complex that results in G(1)-S arrest. Degradation of p27 is mediated by phosphorylation of Thr-187 of p27, which follows ubiquitination. In this study, we generated two adenoviruses expressing wild-type p27 (ad-p27wt) and mutant p27 (ad-p27mt...
متن کاملStudies of adenovirus-SV40 hybrid viruses. IV. An adenovirus type 2 strain carrying the infectious SV40 genome.
Recent studies'-5 have demonstrated that a number of human adenoviruses are capable of forming intergeneric "hybrids," or transcapsidants,5 with SV40 genetic material when propagated in monkey kidney cells naturally or deliberately contaminated with SV40. Such hybrids were recognized by their ability to induce SV40 T antigen detectable by complement fixation (CF) and immunofluorescent (FA) tech...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1986
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(86)83577-9